New frontiers in chemical biology : enabling drug discovery

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The full text of this article hosted at iucr. If you do not receive an email within 10 minutes, your email address may not be registered, and you may need to create a new Wiley Online Library account. If the address matches an existing account you will receive an email with instructions to retrieve your username. ChemMedChem Volume 6, Issue 9. Read the full text.

Jon Clardy - Chemical Biology and Natural Product Based Drug Discovery

Tools Request permission Export citation Add to favorites Track citation. Share Give access Share full text access. Share full text access. Please review our Terms and Conditions of Use and check box below to share full-text version of article. Abstract RSC, Cambridge Citing Literature. Volume 6 , Issue 9 September 5, Pages Related Information.

Close Figure Viewer. Yet we have sought to have our pages reflect a defining characteristic of most chemical biologists: a willingness to adopt ideas and techniques from across all areas of chemistry and biology and to apply them to understand or manipulate biological systems at the molecular level.

Applications for Activity-based Probes in Drug Discovery

Chemical synthesis: investigating bond-breaking and bond-making processes that drive metabolism in cells and enable the development of chemical tools. Chemical mechanisms in biology: understanding the molecular mechanisms of natural biological systems using chemical and biological techniques. Expanding biology through chemistry: applying small molecules, chemical tools and engineered biomolecules to broaden the scope of biological processes. Expanding chemistry through biology: taking inspiration from biology to discover and develop new frontiers in chemistry.

To mark our anniversary, the editorial team has compiled some highlights of our first year that we feel represent our editorial scope and the diversity of content featured in Nature Chemical Biology. This month's content illustrates a breadth of original research at the interface of chemistry and biology. Two papers demonstrate the utility of combining computational and experimental approaches: in the first, this combined approach is used to understand protein aggregation mechanisms p.


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Chemical tools for protein labeling p. As with our previous issues, these original research contributions have enhanced online content. Our anniversary issue also includes highlights of several frontier areas of chemical biology.

In this issue, we feature a Review article on synthetic biology p. We are also pleased to announce the addition of a new article type, called 'Elements', to the pages of Nature Chemical Biology.

Breakout Discussions - World Pharma Week

Elements, which will appear regularly in print and online, will feature interviews with key people in the chemical biology community and offer insights into places or events that are of general interest to chemists and biologists. In our first Elements piece, we include a recent discussion with Jeremy Knowles, from Harvard University, about his views of chemistry and chemical biology p.

We welcome your ideas for people, places and events to feature in upcoming Elements. As we embark on our second year, we will continue our efforts to deliver the best of chemical biology research and commentary.

Martin Fisher

In the coming year, readers can look forward to the expansion of Nature Chemical Biology , including thematic issues and enhanced involvement with the community. Thanks for sharing our enthusiasm for chemical biology and reading Nature Chemical Biology. Reprints and Permissions.

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Skip to main content. Our editorial scope has been organized around four thematic areas of chemical biology research: Chemical synthesis: investigating bond-breaking and bond-making processes that drive metabolism in cells and enable the development of chemical tools. Rights and permissions Reprints and Permissions.

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